Substantia Nigra - Anatomy

Anatomy

See also: Primate basal ganglia system

The substantia nigra, along with four other nuclei, is part of the basal ganglia. It is the largest nucleus in the midbrain, lying dorsal to the cerebral peduncles. Humans have two substantiae nigrae, one on each side of the midline.

The substantia nigra is divided into two parts: the pars reticulata and pars compacta, which lies medial to the pars reticulata. Sometimes a third region, the pars lateralis, is mentioned, though its is usually classified as part of the pars reticulata. The pars reticulata and the internal globus pallidus are separated by the internal capsule.

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