Cell Types
The striatum is heterogeneous in terms of neurons. It is composed of these neuronal cell types:
- Medium spiny neurons so called due to the presence of spines on the dendrites, and making up 96% of the striatum.
- Deiters' neurons (2%) with large, minimally branched arborizations looking like pallidonigral neurons.
- Cholinergic interneurons (1%). In primates, they are the tonically active neurons, and morphologically entirely different from those observed in rodents. These briefly stop firing in response to behaviorally-salient and reward-related events.
- GABAergic parvalbumin expressing interneurons, which are fast-spiking, and express dopamine receptors.
- GABAergic calretinin expressing interneurons.
- GABAergic somatostatin expressing interneurons, which are low-threshold-spiking and express dopamine receptors.
Read more about this topic: Striatum
Famous quotes containing the words cell and/or types:
“Let man consider what he is in comparison with all existence; let him regard himself as lost in this remote corner of nature; and from the little cell in which he finds himself lodged, I mean the universe, let him estimate at their true value the earth, kingdoms, cities, and himself. What is a man in the infinite?”
—Blaise Pascal (1623–1662)
“Science is intimately integrated with the whole social structure and cultural tradition. They mutually support one other—only in certain types of society can science flourish, and conversely without a continuous and healthy development and application of science such a society cannot function properly.”
—Talcott Parsons (1902–1979)