Strecker Amino Acid Synthesis - Asymmetric Strecker Reactions

Asymmetric Strecker Reactions

The asymmetric Strecker reaction was poineered by Kaoru Harada in 1963. By replacing ammonia with (S)-alpha-phenylethylamine as chiral auxiliary the ultimate reaction product was chiral alanine. The first asymmetric synthesis via a chiral catalyst was reported in 1996.

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