Sticky And Blunt Ends
DNA end or sticky end refers to the properties of the end of a molecule of DNA or a recombinant DNA molecule. The concept is important in molecular biology, especially in cloning or when subcloning inserts DNA into vector DNA. All the terms can also be used in reference to RNA. The sticky ends or cohesive ends form base pairs. Any two complementary cohesive ends can anneal, even those from two different organisms. This bondage is temporary however, and DNA ligase will eventually form a covalent bond between the sugar-phosphate residue of adjacent nucleotides to join the two molecules together.
Read more about Sticky And Blunt Ends: Single-stranded DNA Molecules, Variations in Double-stranded Molecules, Discovery, References
Famous quotes containing the words sticky, blunt and/or ends:
“The kiss. There are all sorts of kisses, lad, from the sticky confection to the kiss of death. Of them all, the kiss of an actress is the most unnerving. How can we tell if she means it or if she’s just practicing?”
—Ruth Gordon (1896–1985)
“Devouring Time, blunt thou the lion’s paws,
And make the earth devour her own sweet brood;
Pluck the keen teeth from the fierce tiger’s jaws,
And burn the long-liv’d phoenix in her blood;
Make glad and sorry seasons as thou fleet’st,
And do what’er thou wilt, swift-footed Time,
To the wide world and all her fading sweets;”
—William Shakespeare (1564–1616)
“A needless Alexandrine ends the song,
That, like a wounded snake, drags its slow length along.”
—Alexander Pope (1688–1744)