Sticky And Blunt Ends
DNA end or sticky end refers to the properties of the end of a molecule of DNA or a recombinant DNA molecule. The concept is important in molecular biology, especially in cloning or when subcloning inserts DNA into vector DNA. All the terms can also be used in reference to RNA. The sticky ends or cohesive ends form base pairs. Any two complementary cohesive ends can anneal, even those from two different organisms. This bondage is temporary however, and DNA ligase will eventually form a covalent bond between the sugar-phosphate residue of adjacent nucleotides to join the two molecules together.
Read more about Sticky And Blunt Ends: Single-stranded DNA Molecules, Variations in Double-stranded Molecules, Discovery, References
Famous quotes containing the words sticky, blunt and/or ends:
“The kiss. There are all sorts of kisses, lad, from the sticky confection to the kiss of death. Of them all, the kiss of an actress is the most unnerving. How can we tell if she means it or if she’s just practicing?”
—Ruth Gordon (1896–1985)
“A multitude of causes unknown to former times are now acting with a combined force to blunt the discriminating powers of the mind, and unfitting it for all voluntary exertion to reduce it to a state of almost savage torpor.”
—William Wordsworth (1770–1850)
“If you take away ideology, you are left with a case by case ethics which in practise ends up as me first, me only, and in rampant greed.”
—Richard Nelson (b. 1950)