ST2 Cardiac Biomarker - Correlation With Mortality

Correlation With Mortality

Published and peer-reviewed evidence has indicated that ST2 is a predictor of mortality at presentation. Studies have shown patients with ST2 levels above a clinical threshold consistently have a much higher risk of mortality while, equally important, patients with ST2 levels below threshold have a very low risk of mortality. Although it has been shown that ST2 concentrations correlate with heart failure severity there is no level that perfectly separates patients with and without heart failure for disease diagnosis. However as a prognostic marker it has been clearly shown that patients are at a higher risk of adverse outcomes when ST2 levels are above a cutoff value of 35 ng/mL.