Spontaneous Cerebrospinal Fluid Leak - Causes - Other Causes

Other Causes

Patients with a nude (absent) nerve root are at increased risk for developing recurrent CSF leaks. Cranial CSF leaks are as a result of intracranial hypertension in a vast majority of cases. The increased pressure causes a rupture of the cranial dura mater, leading to CSF leak and intracranial hypotension. Lumbar disc herniation has been reported to cause CSF leak in at least one case. Degenerative spinal disc diseases cause a disc to pierce the dura mater, leading to a CSF leak.

Another view of the cause of orthostatic headaches proposes a malformed distribution of craniospinal elasticity as a result of the collapse of the lower spine's CSF space resulting in the collapse of the dura sac.

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