Indirect Manipulation of Specific Appetite
Specific appetite can be indirectly induced under experimental circumstances. In one study, normal (sodium-replete) rats exposed to angiotensin II via infusion directly into the brain developed a strong sodium appetite which persisted for months. However, the conclusions of this experiment have been contested. Nicotine implants in rats have been shown to induce a specific appetite for sucrose, even after removal of the implants.
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