Souris (French for mouse) can refer to several things:
- The Souris or Mouse River in Canada and the USA
- The Canadian Souris (electoral district)
- The town of Souris, Manitoba, Canada
- The town of Souris, North Dakota, USA
- The town of Souris, Prince Edward Island, Canada
- Family name
- André Souris, Belgian composer
- Georgios Souris, Greek poet
- George Souris, Australian politician