Sook may refer to:
- Sook, Sabah, a small town in Interior Division, Sabah, Malaysia
- Cry baby
- Glynko da Sook, powerlifter
- Hoon Sook Pak, ballerina
- Moon Nam Sook, Korean voice actor
- Ryan Sook, comic book artist
- Suki Low Sook Yee, winner in the One in a Million competition
- Yoo Eun Sook, Korean voice actor
- Jeanne A Sook, professional ice skater, Ice Capades
- Matthew Attwell
- The Chesapeake Bay waterman's term for the female of the blue crab, Callinectes sapidus . Males are jimmies.
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