Sodium Thiopental - Contraindications

Contraindications

Thiopental should not be given in case of liver disease, Addison's disease, myxedema, severe heart disease, severe hypotension, a severe breathing disorder, or a history of porphyria.

Co-administration of pentoxifylline and thiopental causes death by acute pulmonary edema in rats. This pulmonary edema was not mediated by cardiac failure or by pulmonary hypertension but was due to increased pulmonary vascular permeability.