Sodium Cyclamate - Health

Health

In the United States, the U.S. Food and Drug Administration (FDA) banned the sale of cyclamate in 1970 after lab tests in rats involving a 10:1 mixture of cyclamate and saccharin indicated that large amounts of cyclamates causes bladder cancer, a disease to which rats are particularly susceptible. Cyclamates are still used as sweeteners in many parts of the world, including Europe.

A 2003 "paper reports the first epidemiological study designed to investigate the possibility of a relationship between cyclamate and cyclohexylamine and male fertility in humans." It states that "the results demonstrate no effect of cyclamate or cyclohexylamine on male fertility at the present levels of cyclamate consumption."

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