Sodium-iodide Symporter
The sodium/iodide symporter (NIS), also known as Sodium/iodide cotransporter or solute carrier family 5, member 5 (SLC5A5) is a protein that in humans is encoded by the SLC5A5 gene. The sodium/iodide symporter is a transmembrane glycoprotein with a molecular weight of 87 kDa and 13 transmembrane domains, which transports two sodium cations (Na+) for each iodide anion (I–) into the cell. NIS mediated uptake of iodide into follicular cells of the thyroid gland is the first step in the synthesis of thyroid hormone.
Read more about Sodium-iodide Symporter: Iodine Uptake, Inhibition, Regulation in Iodine Uptake, NIS in Thyroid Diseases, Use of The NIS Gene in Therapies With Radioiodine (131I), See Also