Gene Ontology | |
---|---|
Molecular function | • RNA cap binding • protein transporter activity |
Cellular component | • nuclear pore • cytosol |
Biological process | • spliceosomal snRNP assembly • protein import into nucleus • gene expression • RNA metabolic process • ncRNA metabolic process • snRNA import into nucleus |
Sources: Amigo / QuickGO |
75.89 – 75.92 Mb
56.95 – 56.98 Mb
Snurportin-1 is a protein that in humans is encoded by the SNUPN gene.
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.