Isolation
Investigations were conducted in the 1970s and 1980s to search for infectious agents that cause or contribute to a severe ulcerative disease, known as epizootic ulcerative syndrome (EUS), which causes high mortalities among a variety of fish species in Asia and the Pacific region. SNRV was isolated by virologist W. Wattanavijarn from a snakehead murrel, Channa striata (formerly Ophicepahalus striatus), a species of snakehead fish, which exhibited signs of epizootic ulcerative syndrome following an outbreak of this syndrome in Thailand. The new viral isolate was identified as a rhabdovirus based on images and measurements taken via transmission electron microscopy and biochemical test results. Plaque neutralization tests and immunofluorescence tests demonstrated that the new isolate was serologically unrelated to several other fish rhabdoviruses, including anquilla rhabdovirus (EVX), infectious hematopoietic necrosis virus (IHNV), pike fry rhabdovirus (PFRV), spring viremia of carp virus (SVCV), and viral hemorrhagic septicemia virus (VHSV). Subsequent infection studies exposing healthy snakehead murrels from a susceptible population to SHNV did not develop clinical signs associated with EUS, suggesting that SHRV does not play a significant role in EUS.
Read more about this topic: Snakehead Rhabdovirus
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