Small nucleolar RNA SNORA11 (also known as U107) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifiying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA).
U107 has a predicted hairpin-hinge-hairpin-tail structure and is predicted to be a member of the H/ACA box class of snoRNAs that guide the sites of modification of uridines to pseudouridines. This snoRNA was identified by RT-PCR from blood cells and its expression confirmed by Northern blot analysis. There is no predicted RNA target for this guide snRNA.
Famous quotes containing the word small:
“We must remain as close to the flowers, the grass, and the butterflies as the child is who is not yet so much taller than they are. We adults, on the other hand, have outgrown them and have to lower ourselves to stoop down to them. It seems to me that the grass hates us when we confess our love for it.—Whoever would partake of all good things must understand how to be small at times.”
—Friedrich Nietzsche (1844–1900)