Small nucleolar RNA R43 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA R43 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. Plant snoRNA R43 was identified in a screen of Arabidopsis thaliana.
Famous quotes containing the word small:
“It were sad to gaze on the blessèd and no man I loved of old there;
I throw down the chain of small stones! when life in my body has ceased,
I will go to Caoilte, and Conan, and Bran, Sceolan, Lomair,
And dwell in the house of the Fenians, be they in flames or at feast.”
—William Butler Yeats (1865–1939)