Small nucleolar RNA R20 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA R20 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. Plant snoRNA R20 was identified in a screen of Arabidopsis thaliana.
Famous quotes containing the word small:
“For a small child there is no division between playing and learning; between the things he or she does “just for fun” and things that are “educational.” The child learns while living and any part of living that is enjoyable is also play.”
—Penelope Leach (20th century)