Small nucleolar RNA R20 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA R20 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. Plant snoRNA R20 was identified in a screen of Arabidopsis thaliana.
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“To get time for civic work, for exercise, for neighborhood projects, reading or meditation, or just plain time to themselves, mothers need to hold out against the fairly recent but surprisingly entrenched myth that “good mothers” are constantly with their children. They will have to speak out at last about the demoralizing effect of spending day after day with small children, no matter how much they love them.”
—Wendy Coppedge Sanford. Ourselves and Our Children, by Boston Women’s Health Book Collective, introduction (1978)