Small nucleolar RNA Me28S-Cm3227 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Me28S-Cm3227 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. It is predicted that this family directs 2'-O-methylation of 28S C-3227.
Famous quotes containing the word small:
“If Montaigne is a man in the prime of life sitting in his study on a warm morning and putting down the sum of his experience in his rich, sinewy prose, then Pascal is that same man lying awake in the small hours of the night when death seems very close and every thought is heightened by the apprehension that it may be his last.”
—Cyril Connolly (1903–1974)