Small nucleolar RNA Me28S-Am2589 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Me28S-Am2589 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. It is predicted that this family directs 2'-O-methylation of 28S A-2589.
Famous quotes containing the word small:
“Much wondering to see upon all hands, of wattles and woodwork made,
Your bell-mounted churches, and guardless the sacred cairn and the rath,
And a small and a feeble populace stooping with mattock and spade,
Or weeding or ploughing with faces a-shining with much-toil wet;
While in this place and that place, with bodies unglorious, their chieftains stood....”
—William Butler Yeats (1865–1939)