Small nucleolar RNA Me18S-Um1356 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Me18S-Um1356 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. It is predicted that this family directs 2'-O-methylation of 18S U-1356.
Famous quotes containing the word small:
“He bends to the order of the seasons, the weather, the soils and crops, as the sails of a ship bend to the wind. He represents continuous hard labor, year in, year out, and small gains. He is a slow person, timed to Nature, and not to city watches. He takes the pace of seasons, plants and chemistry. Nature never hurries: atom by atom, little by little, she achieves her work.”
—Ralph Waldo Emerson (1803–1882)