Small nucleolar RNA Me18S-Gm1358 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Me18S-Gm1358 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. It is predicted that this family directs 2'-O-methylation of 18S G-1358.
Famous quotes containing the word small:
“My consolation is to think of the women I have known, now that there is no longer such thing as elegance. But how can people who contemplate these horrible creatures under their hats covered in pigeon-houses or gardens, how can they understand the charm of seeing Madame Swann wearing a simple mauve cap or a small hat surmounted by a straight iris?”
—Marcel Proust (1871–1922)