Small nucleolar RNA J33 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA J33 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. Plant snoRNA J33 was identified in a screen of Oryza sativa.
Famous quotes containing the word small:
“When parents fail to set appropriate limits, children may feel more vulnerable at night: the aggressive urges that have not been “tamed” by day may be terrifying to a small child alone in the dark.”
—Cathy Rindner Tempelsman (20th century)