Sleep and Learning - Electrophysiological Evidence in Rats

Electrophysiological Evidence in Rats

A 2009 study based on electrophysiological recordings of large ensembles of isolated cells in the prefrontal cortex of rats revealed that cell assemblies that formed upon learning were more preferentially active during subsequent sleep episodes. More specifically, those replay events were more prominent during slow wave sleep and were concomittant with hippocampal reactivation events. This study has shown that neuronal patterns in large brain networks are tagged during learning so that they are replayed, and supposedly consolidated, during subsequent sleep.

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