SKP2

SKP2

Identifiers Symbols SKP2; FBL1; FBXL1; FLB1; p45 External IDs OMIM: 601436 MGI: 1351663 HomoloGene: 55942 GeneCards: SKP2 Gene

Gene Ontology
Molecular function	• ubiquitin-protein ligase activity • protein binding • identical protein binding
Cellular component	• nucleoplasm • cytosol • SCF ubiquitin ligase complex
Biological process	• G1 phase of mitotic cell cycle • G1/S transition of mitotic cell cycle • S phase of mitotic cell cycle • G2/M transition of mitotic cell cycle • protein polyubiquitination • mitotic cell cycle • cell proliferation • anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process • positive regulation of intracellular estrogen receptor signaling pathway • positive regulation of smooth muscle cell proliferation • regulation of cell cycle • cellular response to cell-matrix adhesion
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 6502 27401 Ensembl ENSG00000145604 ENSMUSG00000054115 UniProt Q13309 Q9Z0Z3 RefSeq (mRNA) NM_001243120 NM_013787 RefSeq (protein) NP_001230049 NP_038815 Location (UCSC) Chr 5:
36.15 – 36.18 Mb Chr 15:
9.11 – 9.14 Mb PubMed search

S-phase kinase-associated protein 2 is an enzyme that in humans is encoded by the SKP2 gene.