Sithole is a surname, and may refer to:
- Moses Sithole, South African serial killer
- Ndabaningi Sithole, Zimbabwean politician
- Robert Sithole, South African musician.
| This page or section lists people with the surname Sithole. If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link. |