The Sinclair Method is a treatment for alcoholism that involves the use of opiate antagonists such as naltrexone or nalmefene while continuing normal drinking habits in order to decrease the craving for alcohol over time. It relies upon a mechanism called pharmacological extinction, which works by blocking the positive reinforcement effects of ethanol-triggered endorphin in the brain. Proponents claim that thousands of patients have been cured by the Sinclair Method since the early 1990s.
Read more about Sinclair Method: Treatment, Theory, Evidence of Efficacy, History, Obstacles
Famous quotes containing the words sinclair and/or method:
“An involuntary return to the point of departure is, without doubt, the most disturbing of all journeys.”
—Iain Sinclair (b. 1943)
“I have a new method of poetry. All you got to do is look over your notebooks ... or lay down on a couch, and think of anything that comes into your head, especially the miseries.... Then arrange in lines of two, three or four words each, don’t bother about sentences, in sections of two, three or four lines each.”
—Allen Ginsberg (b. 1926)