Significance Analysis of Microarrays - Basic Protocol

Basic Protocol

  • Perform microarray experiments — DNA microarray with oligo and cDNA primers, SNP arrays, protein arrays, etc.
  • Input Expression Analysis in Microsoft Excel — see below
  • Run SAM as a Microsoft Excel Add-Ins
  • Adjust the Delta tuning parameter to get a significant # of genes along with an acceptable false discovery rate (FDR)) and Assess Sample Size by calculating the mean difference in expression in the SAM Plot Controller
  • List Differentially Expressed Genes (Positively and Negatively Expressed Genes)

Read more about this topic:  Significance Analysis Of Microarrays

Famous quotes containing the word basic:

    For a novelist, a given historic situation is an anthropologic laboratory in which he explores his basic question: What is human existence?
    Milan Kundera (b. 1929)