As A Surname
- Sir John Shelton, head of the household of the future Queen Elizabeth I of England
- Anne Shelton (courtier), aunt of Anne Boleyn and mother of Henry VIII's mistress, Mary Shelton; wife of the above
- Anne Shelton (singer), British singer
- Blake Shelton, American country singer
- Chris Shelton (baseball player), Major League Baseball player for the Texas Rangers
- Deborah Shelton, US-American actress and star of US soap Dallas
- Ernie Shelton, American high jumper
- George M. Shelton, Philippine-American War Medal of Honor recipient
- Gilbert Shelton, US-American comic artist
- Henry H. Shelton, Retired US Army four star general and former Chairman of the Joint Chiefs of Staff
- Herbert M. Shelton, Prominent American health educator, pacifist, vegetarian, and advocate of raw foodism and fasting cures.
- Ian Shelton, Canadian astronomer
- Ian Shelton (footballer) Australian rules footballer with Essendon Football Club
- John Skelton, also written as John Shelton, poet and tutor of Henry VIII
- Lee Shelton, convicted murder immortalized in song as Stagger Lee
- Luton Shelton (footballer) Jamaican footballer
- Marley Shelton and Samantha Shelton, US-American actress siblings
- Mary Shelton, lady-in-waiting, poetess and mistress of Henry VIII of England
- Peter L. Shelton, architect and interior designer
- Richard Shelton, US-American poet and author
- Ron Shelton, US-American film director
- Rudyard Shelton, fictional character from Darwin's Soldiers.
- Thomas Shelton (translator), British translator of Cervantes
- Thomas Shelton (stenographer)
- Tracey Shelton, photojournalist
- William L. Shelton, US Air Force Lieutenant General
- Ricky Van Shelton, US-American country music singer
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