SF3 may refer to:
- Street Fighter III, a video game
- Shining Force 3, a video game
- Star Fox Adventures, the third game in the Star Fox series
- The Saab 340 turboprop airplane
- The Society for the Furtherance of the Study of Fantasy and Science Fiction or (SF)3, the Wisconsin not-for-profit literary organization which puts on WisCon
- Syphon Filter 3, a video game