Surname
- A. J. Seymour, Guyanese writer
- Alan Seymour, Australian playwright and writer
- Beauchamp Seymour, 1st Baron Alcester, British admiral
- Benjamin Seymour, Canadian politician
- Brett Seymour, Australian rugby league player
- Carolyn Seymour, English actress
- Charles Seymour, American historian
- Charles Seymour, 6th Duke of Somerset
- Cy Seymour, American baseball player
- David Seymour, the American photographer Chim
- Edward Seymour, 1st Duke of Somerset and successors
- Edward Seymour, several people
- Elizabeth Seymour, Marchioness of Winchester, sister of Queen Jane, the third wife of Henry VIII of England
- Elizabeth Seymour, Duchess of Somerset (1667–1722), Whig politician
- Felipe Seymour, Chilean football player
- Forrest W. Seymour (journalist), American journalist
- Frances Ford Seymour, mother of Jane Fonda and Peter Fonda
- Frederick Seymour, governor of British Columbia
- Gerald Seymour, British writer
- Gordon Seymour, pseudonym of Charles Waldstein
- Henry Seymour, several people
- Hezekiah C. Seymour, NYS Engineer and Surveyor 1850–1851
- Horatio Seymour (1810–1886), Governor of New York
- Horatio Seymour, Jr. (1844–1901), NYS Engineer and Surveyor 1878–1881, nephew of Gov. Horatio Seymour
- Horatio Seymour (Vermont), American politician and senator from Vermont
- Lord Hugh Seymour (1759-1801), British naval officer
- James Seymour, British artist
- James Benjamin Seymour (1869–1950), of England
- James M. Seymour, Sr., mayor of Newark, New Jersey
- Jane Seymour, third wife of Henry VIII, King of England
- Jane Seymour (actress), actress known by this stage name
- John Seymour, several people including
- John Seymour (Tudor), father of Elizabeth, Jane and Thomas
- John F. Seymour, American politician
- Kelly Seymour, South African cricketer
- Kevin Seymour, Australian businessman and founder of Seymour Group
- Mark Seymour, Australian musician
- Mary Seymour (Chatsworth) (born 1548), daughter of Catherine Parr and Thomas, 1st Baron Seymour of Sudeley
- Michel Seymour, Québécois philosopher and professor
- Michael Seymour, several people including:
- Sir Michael Seymour, 1st Baronet (1768–1834), British naval commander
- Michael Seymour (Royal Navy officer) (1802–1887), British naval commander, son of the above
- Michael Seymour (production designer), production designer
- Miranda Seymour, English writer
- Nick Seymour, Australian bass guitarist
- Paul Seymour (mathematician), mathematician
- Paul Seymour (basketball), American basketball player and coach
- Richard Seymour, American football player
- Richard Seymour (writer), British writer
- Silas Seymour (1817–1890), NYS Engineer and Surveyor 1856–1857 and 1882–1883
- Stephanie Kulp Seymour (born 1940), U.S. court of appeals judge
- Stephanie Seymour (born 1968), supermodel
- Terri Seymour, British television presenter and sometime actress
- Thomas Seymour, 1st Baron Seymour of Sudeley, brother of Jane Seymour
- Thomas Day Seymour, American classical scholar
- Truman Seymour, American Civil War general and painter
- William Seymour, several people including:
- William Kean Seymour (1887–1975), British writer
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