Serre may refer to:
- Claude Serre (1938–1998), a French cartoonist
- Jean-Pierre Serre (1926–), a French mathematician active in algebraic geometry, number theory and topology
- Serre (grape), a red Italian wine grape
- Serre Chevalier, a major French ski resort in the southern part of the Alps
- Serre (river), a tributary of the Oise in France
- Serre, Campania, a town and comune in the province of Salerno in the Campania region of south-western Italy
- Serre Calabresi, a mountain and hill area of Calabria, Italy
- a greenhouse in French, like in the Jardin Serre de la Madone park in Menton, Alpes-Maritimes, Provence-Alpes-Côte d'Azur, France