Septic, when derived from the Greek Σήψις ('putrefaction'), may refer to:
- Septic shock
- Septic tank or septic system, a component of a small scale sewage disposal system
- Cockney rhyming slang for American, coming from "Septic Tank"(i.e. Yank)
Septic, when derived from the Greek ἑπτά or Latin septem ('seven'), may refer to:
- Septic equation, a polynomial of degree seven