SEP15 - Protein Domain

Protein Domain

Sep15

Solution structure of SelM from Mus musculus
Identifiers
Symbol Sep15_SelM
Pfam PF08806
InterPro IPR014912
Available protein structures:
Pfam structures
PDB RCSB PDB; PDBe
PDBsum structure summary

The protein this gene encodes for is often called Sep15 however in the case of mice, it is named SelM. This protein is an selenoprotein only found in eukaryotes. This domain has a thioredoxin-like domain and a surface accessible active site redox motif. This suggests that they function as thiol-disulfide isomerases involved in disulfide bond formation in the endoplasmic reticulum.

Read more about this topic:  SEP15

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