Selective Internal Radiation Therapy - Adverse Effects

Adverse Effects

Complications include postradioembolization syndrome (PRS), hepatic dysfunction, biliary complications, portal hypertension, radiation pneumonitis, gastrointestinal ulcers, vascular injury, and lymphopenia.

Postradioembolization syndrome (PRS) includes fatigue, nausea, vomiting, anorexia, fever, abdominal discomfort, and cachexia, occurring in 20-55% of patients. Steroids and antiemetic agents may decrease the incidence of PRS.

Biliary complications include cholecystitis and biliary strictures.

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