Current Research
Seattle BioMed performs research on four areas of infectious disease:HIV/AIDS, malaria, tuberculosis (TB), and Emerging & Neglected Diseases (END) like African sleeping sickness, leishmaniasis, Chagas disease, and toxoplasmosis. Seattle is a hub for global health research, and in July 2012, Seattle Magazine honored two Seattle BioMed leaders (Dr. Stuart and Theresa Britschgi, Director of BioQuest) as "Top Docs" for the work they're doing in research and scientific training.
As part of a broad global initiative to fight malaria, Seattle BioMed developed its malaria program in 2000, with an initial grant from the Bill & Melinda Gates Foundation. With a three-pronged approach, Seattle BioMed's malaria program is focused on vaccine discovery for pregnancy malaria, severe malaria in children, and liver-stage malaria. In 2005, Seattle BioMed received two Grand Challenges in Global Health grants to accelerate its malaria research. And in 2011, Seattle BioMed was granted another $9 million from the Foundation to support malaria vaccine efforts.
In 2010, Dr. Stefan Kappe developed his own malaria vaccine candidate which is a weakened form of the malaria parasite, and that vaccine candidate is undergoing clinical trials at Walter Reed near Washington, D.C. Soon after, in collaboration with PATH's Malaria Vaccine Initiative, Seattle BioMed became home to one of four malaria clinical trial centers in the world where treatments and vaccines can be safely tested in humans using the human challenge model.
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