SDC may refer to:
- SAARC Documentation Centre, a regional centre of SAARC located at New Delhi in India
- Sassarese language, for which
sdcis the ISO 639-3 code - Selby District Council, a local authority in Selby, England
- Sentosa Development Corporation, a statutory board in Singapore
- Sheffield Development Corporation, a corporation created in 1988 to regenerate Sheffield, England
- San Diego Chargers, a football team
- Societas Doctrinæ Christianæ (Society of Christian Doctrine)
- Silver Dollar City, a theme park in Branson, Missouri.
- Stage Directors and Choreographers Society, a U.S. labor union governing theatrical directors and choreographers
- Street Drum Corps, a band from Los Angeles, California, USA
- Summer Doldrums Competition, The Totally Official Summer Doldrums Competition
- Sussex Downs College, a large college in the South East of England
- Sustainable Development Commission, the UK Government’s watchdog on sustainable development
- Swiss Agency for Development and Cooperation
- System Development Charges, more commonly known as Impact Fees, charged to real estate developers to fund public services
- Computing and technology
- Secure Download Cabinet, a software packaging format used by Microsoft
- Silent data corruption, a threat to the correctness of customer data caused by soft errors
- Smart Data Compression, a type of GIS data format
- Society of Dyers and Colourists, an international professional society specialising in colour
- Spirit DataCine, a telecine/motion picture film scanner
- Synopsys Design Constraints, a constraint specification format for digital electronic design.
- System Development Corporation, a computer manufacturer