Schuylkill may refer to the
- Schuylkill River, Pennsylvania, United States
- Places
- Schuylkill, Philadelphia, Pennsylvania, neighborhood in South Philadelphia
- Schuylkill Expressway, portion of I-76 in Philadelphia
- Schuylkill County, Pennsylvania
- Schuylkill Township, Chester County, Pennsylvania
- Schuylkill Township, Schuylkill County, Pennsylvania
- Other
- USS Schuylkill (AO-76)
- Schuylkill Branch, rail line
- Schuylkill Regional Medical Center
- a train operated by Amtrak as part of the Clocker service