Scavenger Receptor - Function

Function

It is thought that scavenger receptors participate in the removal of many foreign substances and waste materials in the living body by extensive ligand specificity and a variety of receptor molecules.

In atherosclerotic lesions, macrophages that express scavenger receptors on their plasma membrane aggressively uptake the oxidized LDL deposited in the blood vessel wall inside and become foam cells, and they secrete various inflammatory cytokines and accelerate the development of atherosclerosis.

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