SBR may refer to:
- Samuel Butler Room, the Middle Combination Room of St John's College, Cambridge
- Saturable Bragg reflector, laser optics, mode locking, Kerr lens effect
- SBR Creative Media, a radio station consultant and advising business
- Sea-based Radar, a United States Government floating, self-propelled, mobile radar station designed to roam over the Pacific Ocean to detect incoming ballistic missiles
- Sequencing batch reactor, waste water treatment process through oxygenation
- Shanghai Business Review, a monthly Shanghai business magazine
- Short-barreled rifle, a rifle with a barrel length of less than 16 inches as designated by the BATFE
- Sir Bobby Robson, an English football manager
- Skills based routing, a call assignment strategy used in call centres
- South Bay Riders, a motorcycle member group and forum based in Northern California.
- Space-Based Radar, both the name of a specific U.S. Air Force project, and of a concept in general for placing satellites into Earth orbit with the ability to track airborne, seaborne, and land-based targets
- Spectral band replication, a technology to enhance audio or speech codecs especially at low bit rates
- Standard Business Reporting, a group of international programs instigated by a number of governments to reduce the regulatory burden for businesses
- Station biologique de Roscoff, a marine research laboratory in France
- Steel Ball Run, a Japanese comic by Hirohiko Araki
- Stone Brothers Racing, a premier Ford team in the Australian V8 Supercar Championship
- Stratford on Avon and Broadway Railway
- Styrene-butadiene rubber, a kind of synthetic rubber
- Sportsbook Review, a site that reviews sportsbooks
- Summit Bechtel Reserve, short name for The Summit Bechtel Family National Scout Reserve
- Statement-based replication, a method of replicating databases available in MySQL