Santenay may refer to the following communes in France:
- Santenay, Côte-d'Or
- Santenay, Loir-et-Cher
It may also refer to:
- Santenay AOC, a wine classification based on the town of the same name in Côte-d'Or
- Ensemble Santenay, a musical ensemble specialising in music from the 14th and 15th Centuries.