Sandbox may refer to:
- Litter box, an indoor box for cats to relieve themselves
- Sandpit or sandbox, a wide, shallow playground construction to hold sand often made of wood or plastic
- Sandbox (locomotive), a container that holds sand for use in improving rail adhesion in slippery conditions
- Sand box (civil engineering), a device to remove centring
- The Sandbox (play), a 1960 one-act play by Edward Albee
- Sandbox (missile) or SS-N-12, a Soviet anti-ship missile
- A container for sand or pounce (calligraphy), used before blotting paper
- Sandbox Therapy, a tool used by child psychologists
- A slang name for the Middle East, used by the American military
- Sandbox Tree, an evergreen tree
- The Sandpit, the Prix Ars Electronica Award of Distinction 2010 winning video art piece by Sam O'Hare
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