Semi-synthetic Analogues
Research on salvinorin derivatives has produced a number of semi-synthetic compounds, several of which can be conveniently made from salvinorin B. Most derivatives are selective kappa opioid agonists as with salvinorin A, although some are even more potent, with the most potent compound 2-ethoxymethyl salvinorin B being 10x stronger than salvinorin A. A few derivatives such as herkinorin have reduced kappa opioid action and instead act as mu opioid agonists.
- 2-Methoxymethyl Salvinorin B
Read more about this topic: Salvinorin A
Famous quotes containing the word analogues:
“It seems to me that we do not know nearly enough about ourselves; that we do not often enough wonder if our lives, or some events and times in our lives, may not be analogues or metaphors or echoes of evolvements and happenings going on in other people?—or animals?—even forests or oceans or rocks?—in this world of ours or, even, in worlds or dimensions elsewhere.”
—Doris Lessing (b. 1919)