Viral Replication Cycle
Both the (+) and the (–) strands of L-A are synthesized within viral particles. Mature particles containing L-A dsRNA synthesize (+) strands (transcription) by a conservative mechanism, and extrude the new strand from the particles. These (+) strands serve as mRNA, to make coat proteins, and as the species encapsidated by those proteins to make new nucleoprotein particles. Encapsidated (+) strands are converted to dsRNA form (replication). The absence of both 5′ cap and 3′ poly(A) on the viral mRNA is the basis of complex interactions of virus and host in translation.
Read more about this topic: Saccharomyces Cerevisiae Virus L-A
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