RZ can stand for:
- ASEA Rz, a Swedish test locomotive
- Return-to-zero
- Rachel Zoe, an American fashion stylist
- Raquel Zimmermann, a Brazilian model
- Redneck Zombies, a 1986 horror film
- Renée Zellweger, an American actress
- Richard Zednik, a Slovak professional hockey player
- Rob Zombie, an American heavy metal artist and film director
- Robert Zemeckis, an American filmmaker
- Robert Zimmerman (disambiguation)
- Robin Zander, an American rock singer with Cheap Trick
- Roger Zelazny, an American Science fiction and fantasy writer
- Ron Ziegler, a White House Press Secretary under Richard Nixon
- Ron Zimmerman (comics), an American television writer
- Ronnie Van Zant, an American classic rock frontman with Lynyrd Skynyrd
- Rz (digraph), a digraph of the Polish alphabet
- Revolutionary Cells (RZ)