Mouse Knockout
Mice embryos with homozygous mutations on RUNX1 died at about 12.5 days. The embryos displayed lack of fetal liver hematopoiesis.
Similar experiments from a different research group demonstrated that the knockout embryos die between embryonic days 11.5 and 12.5 due to hemorrhaging in the central nervous system (CNS).
Read more about this topic: RUNX1
Famous quotes containing the word mouse:
“It is as when a migrating army of mice girdles a forest of pines. The chopper fells trees from the same motive that the mouse gnaws them,—to get his living. You tell me that he has a more interesting family than the mouse. That is as it happens.”
—Henry David Thoreau (1817–1862)