RPF is a three-letter abbreviation that may refer to:
- Railway Protection Force, India
- Raspberry Pi Foundation a charity whose goal is to promote the study of basic computer science in schools. Developers of the Raspberry PI
- Rassemblement du Peuple Français, a former French political party
- Rassemblement pour la France, a French political party
- Real person fiction, a literary genre
- Reformatorische Politieke Federatie, a former Dutch political party
- Regenerative Particulate Filter, see Diesel particulate filter
- The Rehabilitation Project Force of the Church of Scientology
- Renal plasma flow, in medicine
- Retroperitoneal fibrosis, a disease
- Reverse path forwarding, for both Unicast and Multicast routing
- Raster Product Format, a series of GIS file formats used in digital mapping
- Richard P. Feynman, physicist, drummer, artist
- Rwandan Patriotic Front, political party responsible for the rebel incursion which ended the Rwandan Genocide