Robert Woodruff may refer to:
- Robert Woodruff (director), theatre director
- Robert E. Woodruff, president of Erie Railroad 1939–1949
- Robert W. Woodruff, philanthropist and long-time president of The Coca-Cola Company
- Bob Woodruff, television journalist wounded in Iraq in 2006
- Bob Woodruff (American football), George Robert Woodruff, former University of Florida and Baylor University head football coach
- Bob Woodruff (singer)
- Bobby Woodruff, English former footballer