Initiation
Initiation: the construction of the polymerase complex on the promoter. Pol III is unusual (compared to Pol II) requiring no control sequences upstream of the gene, instead normally relying on internal control sequences - sequences within the transcribed section of the gene (although upstream sequences are occasionally seen, e.g. U6 snRNA gene has an upstream TATA box as seen in Pol II Promoters).
Read more about this topic: RNA Polymerase III
Famous quotes containing the word initiation:
“The difficult and risky task of meeting and mastering the new—whether it be the settlement of new lands or the initiation of new ways of life—is not undertaken by the vanguard of society but by its rear. It is the misfits, failures, fugitives, outcasts and their like who are among the first to grapple with the new.”
—Eric Hoffer (1902–1983)
“Until the end of the Middle Ages, and in many cases afterwards too, in order to obtain initiation in a trade of any sort whatever—whether that of courtier, soldier, administrator, merchant or workman—a boy did not amass the knowledge necessary to ply that trade before entering it, but threw himself into it; he then acquired the necessary knowledge.”
—Philippe Ariés (20th century)