RLP may refer to:
- Radio Link Protocol, an automatic repeat request fragmentation protocol used over a wireless (typically cellular) air interface
- Really Likable People, a collection of companies headed by Tom DeLonge of the bands Blink-182 and Angels And Airwaves
- Reel Life Productions, an independent record label founded by rapper Esham
- Research Letters in Physics, an open-access scientific journal
- Resource Location Protocol, used for determining the location of higher level services from hosts on a network
- Randomized Logarithmic-space Polynomial-time, the complexity class of problems solvable by a probabilistic machine in logarithmic space and polynomial time with one-sided error
- Round Ligament Pain, a pain of the round ligament of uterus
- Riverside Long Playing, serial number for Riverside Records LP albums
- Room, Locker, and Personnel inspection, part of basic training of recruits by United States Marine drill instructors.
- 2,3-diketo-5-methylthiopentyl-1-phosphate enolase, an enzyme