In Vivo Versus in Vitro Studies
In vivo studies reveal that Rickettsia rickettsii invade endothelial lining of small to medium vessels in the human host, causing vascular permeability. When tested in vitro, it is shown that the bacterium infects every kind of cell of the mammalian host.
Read more about this topic: Rickettsia Rickettsii
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“The conduct of a man, who studies philosophy in this careless manner, is more truly sceptical than that of any one, who feeling in himself an inclination to it, is yet so over-whelmd with doubts and scruples, as totally to reject it. A true sceptic will be diffident of his philosophical doubts, as well as of his philosophical conviction; and will never refuse any innocent satisfaction, which offers itself, upon account of either of them.”
—David Hume (17111776)